Latest publications in press

Asojo, O.A., Darwiche, R., Gebremedehin, S., Smant, G., Lozano-Torres, J.L., Drurey, C., Pollet, J., Maizels, R.M., Schneiter, R. and Wilbers, R.H.P. (2018) Heligmosomoides polygyrus Venom Allergen-like Protein-4 (HpVAL-4) is a sterol binding protein. International Journal of Parasitology 48: 359-369  Open Access PDF

Darwiche, R., Lugo, F., Drurey, C., Varossieau, K., Smant, G., Wilbers, R.H.P., Maizels, R.M., Schneiter, R. and Asojo, O.A. (2018) Crystal structure of Brugia malayi venom allergen-like protein-1 (Bm-VAL-1), a vaccine candidate for lymphatic filariasis. International Journal of Parasitology 48: 351-358    Open Access PDF

Löser, S. and Maizels, R.M. (2018) Immunology: the nervous pathway to mucosal immunity. Current Biology 17: R33-R36 PDF

Smyth, D.J., Harcus, Y., White, M.P.J., Gregory, W.F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J.P., Ivens, A., McSorley, H.J. and Maizels, R.M. (2018) TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus. International Journal of Parasitology 48: 379-385   Open Access PDF

Recently Published 2017

Coakley, G., McCaskill, J.L., Borger, J.G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H.J., Maizels, R.M. and Buck, A.H. (2017) Extracellular vesicles from a helminth parasite suppress macrophage activation and constitute an effective vaccine for protective immunity. Cell Reports, 19: 1545-1557. PMC5457486     Graphical Abstract     Open Access PDF

Johnston, C.J.C., Smyth, D.J., Kodali, R.B., White, M.P.J., Harcus, Y., Filbey, K.J., Hewitson, J.P., Hinck, C.S., Ivens, A., Kemter, A.M., Kildemoes, A.O., Le Bihan, T., Soares, D., Anderton, S.M., Brenn, T., Wigmore, S.J., Woodcock, H., Chambers, R.C., Hinck, A.P., McSorley, H.J. and Maizels, R.M. (2017) A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. Nature Communications 8:1741  DOI 10.1038/s41467-017-01886-6. Open Access PDF

Ma, G., Holland, C.V., Wang, T., Hofmann, A., Fan, C.K., Maizels, R.M., Hotez, P.J. and Gasser, R.B. (2018) Human toxocariasis. Lancet Infectious Diseases 18:e14-e24 DOI 10.1016/S1473-3099(17)30331-6  PDF

McFarlane, A.J., McSorley, H.J., Davidson, D.J., Fitch, P.M., Errington, C., Mackenzie, K.J., Gollwitzer, E.S, Johnston, C.J.C., MacDonald, A.S., Edwards, M.R., Harris, N.L., Marsland, B.J., Maizels, R.M. and Schwarze, J. (2017) Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota Journal of Allergy and Clinical Immunology 140 : 1068-1078.e6 DOI 10.1016/j.jaci.2017.01.016   PDF

Minutti, C., Blair, N., Schwarz, C., Drube, S., Kamradt, T., Sibilia, M., Fallon, P., Maizels, R.M., and Zaiss, D. (2017) EGF-R expression regulates the antigen-independent function of Th2 cells. Immunity 47 : 710-722  Graphical Abstract        Open Access PDF

Osbourn, M., Soares, D.C., Vacca, F., Cohen, E.S., Scott, I.C., Toivakka, M., Kemter, A., le Bihan, T., Wear, M., Smyth, D.J., Filbey, K.J., Hewitson, J.P., Henderson, J., Gonzàlez, A., Errington, C, Schwarze, J., Ivens, I.C., Maizels, R.M. and McSorley, H.J. (2017) HpARI protein secreted by a helminth parasite suppresses interleukin-33.   Immunity 47: 739-751.    Graphical Abstract    Open Access PDF

Mutapi, F., Maizels, R.M., Fenwick, A., Woolhouse, M. (2017) Human schistosomiasis in the post mass drug administration era. Lancet Infectious Diseases 17: e42-e48  PDF

Pastille, E., Frede, A., McSorley, H.J., Gräb, J. Adamczyk, A,m Kollenda, S., Hansen, W., Epple, M., Buer, J., Maizels, R.M., Klopfleisch, R.,and Westendorf, A.M. (2017) Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer. PLOS Pathogens 13: e1006649 Open Access PDF

Rückerl, D., Campbell, S.M., Duncan, S., Sutherland, T.E., Jenkins, S.J., Hewitson, J.P., Barr, T., Jackson-Jones, L., Maizels, R.M. and Allen, J.E. (2017) Macrophage origin limits functional plasticity in helminth-bacterial co-infection. PLOS Pathogens 13:e1006233. PMC5364000. Open Access PDF

Varyani, F., Fleming, J.O. and Maizels, R.M. (2017). Helminths in the gastrointestinal tract as modulators of immunity and pathology American Journal of Physiology Gastrointestinal and Liver Physiology 312: G537-G549 Open Access PDF 

Maizels Lab Publications 2016 (292-308)

Maizels Lab Publications 2015