Maizels Lab Publications 2016

  1. Coakley, G., Buck, A.H. and Maizels, R.M. (2016) Host parasite communications – messages from helminths for the immune system.Molecular and Biochemical Parasitology 208 : 33-40. doi 10.1016/j.molbiopara.2016.06.003  PMC5008435   Open Access PDF
  2. Duffin, R., O’Connor, R.A., Crittenden, S., Forster, T., Yu, C., Zheng, X., Smyth, D., Robb, C.T., Rossi, F., Skouras, C., Tang, S., Richards, J., Pellicoro, A., Weller, R.B., Breyer,R.M., Mole, D.J., Iredale, J.P., Anderton, S.M., Narumiya, S., Maizels, R.M., Ghazal, P., Howie, S.E., Rossi, A.G. and Yao, C. (2016) Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis. Science 351 : 1333-1338  doi 10.1126/science.aad9903  PMC4841390 Open Access PDF
  3. Gause, W.C. and Maizels, R.M. (2016) Macrobiota – helminths as active participants and partners of the microbiota in host intestinal homeostasis. Current Opinion in Microbiology 32: 14-18. PMC4983462 PDF
  4. Gerbe, F., Sidot, E., Smyth, D.J., Ohmoto, M., Matsumoto, I., Dardalhon, V., Cesses, P., Garnier, L., Bruschi, M. Harcus, Y., Zimmerman, V.S., Taylor, N., Maizels, R.M. and Jay, P. (2016) Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites. Nature 529 : 226-230 doi 10.1038/nature16527. PDF
  5. Hewitson, J.P., Nguyen, D.-L., van Diepen, A., Smit, C.H., Koeleman, C.A., McSorley, H.J., Murray, J., Maizels, R.M. and Hokke, C.H. (2016) Novel O-linked methylated glycans decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus. International Journal of Parasitology 46 : 157-170. PMC4776704 Open Access PDF
  6. Jackson-Jones, L.H., Duncan, S.M., Magalhaes, M.S., Campbell, S., Maizels, R.M., McSorley, H.J., Allen, J.E., and Bénézech, C. (2016) Fat associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nature Communications, 7: 12651 PMC5025788 Open Access PDF
  7. Jackson-Jones, L.H., Rückerl, D.A., Svedberg, F., Duncan, S.M., Maizels, R.M., Sutherland, T.E., Jenkins, S.J., McSorley, H.J., Bénézech, C., MacDonald, A.S. and Allen, J.E. (2016) IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha, European Journal of Immunology 46 : 2311-2321. PMC5082546   Open Access PDF
  8. Johnston, C.J.C., Smyth, D.J., Dresser, D.W. and Maizels, R.M. (2016) TGF-β in tolerance, development and regulation of immunity. Cellular Immunology 299 : 14-22. PMC4711336. 10.1016/j.cellimm.2015.10.006  Open Access PDF
  9. Lundie, R.J., Webb, L.M., Marley, A.K., Phythian-Adams, A.T., Cook, P.C., Jackson-Jones, L.H., Brown, S., Maizels, R.M., Boon, L., O’Keeffe, M. and MacDonald, A.S. (2016) A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection. Immunology and Cell Biology 94 : 400-410. PMC4817239. doi:10.1038/icb.2015.114  Open Access PDF
  10. Maizels, R.M. (2016) Regulatory T cell control of Type 2 Inflammation. In The Th2 Type Immune Response (Eds Gause, W.C. and Artis, D) Springer, pp 73-96.
  11. Maizels, R.M. (2016) Parasitic helminth infections and the control of human allergic and autoimmune disorders. Clinical Microbiology and Infection 22:481-486
  12. Maizels, R.M. and McSorley, H.J. (2016) Regulation of the immune system by helminth parasites. Journal of Allergy and Clinical Immunology 138 : 666-675. PMC5010150
  13. Maizels, R.M. and Hewitson, J.P. (2016). Myeloid cell phenotypes in susceptibility and resistance to parasitic infections. In Myeloid Cells in Health and Disease: a Synthesis (Ed. S. Gordon) pp759-769. Microbiol Spectrum 4: MCHD-0043-2016
  14. Obieglo, K., Feng, X., Bollampalli, V.P., Dellacasa-Lindberg, I., Classon, C., Österblad, M., Helmby, H., Hewitson, J.P., Maizels, R.M., Rothfuchs, A.G., and Nylén, S. (2016). Chronic gastrointestinal nematode infection mutes immune responses to mycobacterial infection distal to the gut. Journal of Immunology, 196 : 2262-2271
  15. Simbari, F., McCaskill, J., Coakley, G., Millar, M., Maizels, R.M., Fabriás, G., Casas, J., and Buck, A.H. (2016) Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications on exosome stability and biology. Journal of Extracellular Vesicles 5: 30741 PMC4937767
  16. Smith, K.A., Filbey, K.J., Reynolds, L.A., Hewitson, J.P., Harcus, Y., Boon, L., Sparwasser, T., Hämmerling, G. and Maizels, R.M. (2016) Low level regulatory T cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths. Mucosal Immunology 9 : 428-443
  17. Smits, H. H., Hiemstra, P. S., Prazeres da Costa, C., Ege, M., Edwards, M., Garn, H., Howarth, P. H., Jartti, T., de Jong, E. C., Maizels, R. M., Marsland, B. J., McSorley, H. J., Muller, A., Pfefferle, P. I., Savelkoul, H., Schwarze, J., Unger, W. W., von Mutius, E., Yazdanbakhsh, M. and Taube, C. (2016). Microbes and asthma: Opportunities for intervention. Journal of Allergy and Clinical Immunology 137 : 690-697