CD44 coreceptor for TGM1 – published in PNAS

August 2023 : Exciting new data showing that TGM1 (H. polygyrus Transforming Growth factor-beta Mimic-1) binds not only the mammalian TGFβ receptors (as shown by Mukundan et al, 2022, doi 10.1016/j.jbc.2022.101994), but also CD44, enhancing potency for induction of regulatory T cells. The outcome of a great collaboration with the laboratories of Peter ten Dijke (Leiden University Medical Center) and Andrew Hinck (University of Pittsburgh).  Download the PDF here!


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