1991
66. Bradley, J.E., Helm, R., Lahaise, M. and Maizels, R.M. (1991) cDNA clones of Onchocerca volvulus low molecular weight antigens provide immunologically specific diagnostic probes. Molecular and Biochemical Parasitology 46 : 219-228
67. Day,K.P., Gregory,W.F. and Maizels, R.M. (1991) Age-specific acquisition of immunity to infective larvae in a Bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunology 13 : 277-290
68. Healer, J., Ashall, F. and Maizels, R.M. (1991) Characterization of proteolytic enzymes from larval and adult Nippostrongylus brasiliensis. Parasitology 103 : 305-314.
69. Khoo, K.-H., Maizels, R.M., Page, A.P., Taylor, G.W., Rendell, N.B. & Dell, A. (1991) Characterisation of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides. Glycobiology 1 : 163-171.
70. Maizels, R.M. and Lawrence, R.A. (1991) Immunological tolerance: the key feature of human filariasis. Parasitology Today 7: 271-276.
71. Maizels, R.M. and Robertson, B.D. (1991) Toxocara canis: Secreted glycoconjugate antigens in immunobiology and immunodiagnosis. In Parasitic Nematodes - Antigens, Membranes and Genes (Ed. Kennedy, M.) Taylor and Francis Ltd, London, pp 95-115
72. Maizels, R.M., Blaxter, M.L., Robertson, B.D. and Selkirk, M.E. (1991) Parasite Antigens, Parasite Genes. A Laboratory Manual for Molecular Parasitology. Cambridge University Press, 224 pp.
73. Maizels, R.M., Kurniawan, A., Selkirk, M.E. and Yazdanbakhsh, M. (1991) Immune responses to filarial parasites. Immunology Letters 30 : 249-254.
74. Page, A.P., Richards, D., Lewis, J., Hussain, O. and Maizels, R.M. (1991) Comparison of isolates and species of Toxocara and Toxascaris by biosynthetic labelling of somatic and ES proteins from infective larvae. Parasitology 103 : 451-464.
1992
75. Adebajo, A.O., Akinsola, A., Maizels, R.M., Cawston, T.E. and Hazleman, B.L. (1992) Rheumatoid factor and rheumatoid factor isotypes on filariasis with and without accompanying glomerulo-nephritis. Transactions of the Royal Society for Tropical Medicine and Hygiene 86 : 667-669.
76. Blaxter, M.L., Page, A.P., Rudin, W. and Maizels, R.M. (1992) Nematode surface coats: actively evading immunity. Parasitology Today 8 : 243-247
77. Haswell-Elkins, M., Leonard, H., Kennedy, M., Elkins, D.B. and Maizels, R.M. (1992) Immuno-epidemiology of Ascaris lumbricoides : Relationships between antibody specificities, exposure and infection in a human community. Parasitology 104: 153-159.
78. Maizels, R.M. and Denham, D.A. (1992) Diethylcarbamazine (DEC): immunopharma-cological interactions of an anti-filarial drug. Parasitology 105 (Suppl.): S49-S60.
79. Maizels, R.M. and Partono, F. (1992) Lymphatic filariasis. Medicine International, 4548-4551
80. Page, A.P. and Maizels, R.M. (1992) Biosynthesis and glycosylation of serine/threonine-rich secreted proteins from Toxocara canis larvae. Parasitology 105 : 297-308
81. Page, A.P., Hamilton, A.J and Maizels, R.M. (1992) Toxocara canis : monoclonal antibodies to carbohydrate epitopes of secreted (TES) antigens localize to different secretion-related structures in infective larvae. Experimental Parasitology 75 : 56-71
82. Page, A.P., Rudin, W. and Maizels, R.M. (1992) Lectin binding to secretory structures, cuticle and surface coat of Toxocara canis infective larvae. Parasitology 105 : 285-296
83. Page, A.P., Rudin, W., Fluri, E., Blaxter, M.L. and Maizels, R.M. (1992) Toxocara canis : a labile antigenic coat overlying the epicuticle of infective lavae. Experimental Parasitology 75 : 72-86
84. Selkirk, M.E., Maizels, R.M. and Yazdanbakhsh, M. (1992) Immunity and the prospects for vaccination against filariasis. Immunobiology 184 : 263-281
1993
85. Bradley, J.E., Tuan, R.S., Shepley, K.J., Tree, T.I.M., Maizels, R.M., Helm, R., Gregory, W.F. and Unnasch, T.R. (1993) Onchocerca volvulus : characterization of an immunodominant hypodermal antigen present in adult and larval parasites. Experimental Parasitology 77: 414-424
86. Gillespie, S.H., Bidwell, D., Voller, A., Robertson, B.D. and Maizels, R.M. (1993) Diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. Journal of Clinical Pathology 46: 551-554
87. Kurniawan, A., Yazdanbakhsh, M., van Ree, R., Aalberse, R., Selkirk, M.E., Partono, F. and Maizels, R.M. (1993) Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. Journal of Immunology 150 : 3941-3950
88. Lewis, J. & Maizels, R.M., Eds. (1993) Toxocara and Toxocariasis: Clinical, Epidemiological and Molecular Perspectives. Institute of Biology, London, 169 pp.
89. Maizels, R.M., Blaxter, M.L. and Selkirk, M.E. (1993) Forms and functions of nematode surfaces. Experimental Parasitology 77: 380-384
90. Maizels, R.M., Bundy, D.A.P., Selkirk, M.E., Smith, D.F. and Anderson, R.M. (1993) Immunological modulation and evasion by helminth parasites in human communities. Nature 365: 797-805
91. Maizels, R.M., Gems, D.H. and Page, A.P. (1993) Synthesis and secretion of Toxocara ES antigens. In Toxocara and Toxocariasis: Clinical, Epidemiological and Molecular Perspectives (Lewis, J. & Maizels, R.M., Eds.) Institute of Biology, London, pp 141-150
92. Paxton, W.A., Yazdanbakhsh, M., Kurniawan, A., Partono, F., Maizels, R.M. and Selkirk, M.E. (1993) Primary structure of and Immunoglobulin E response to the repeat subunit of gp15/400 from human lymphatic filarial parasites. Infection and Immunity 61: 2827-2833
93. Rathaur, S., Müller, S., Maizels, R.M. and Walter, R.D. (1993) Identification of circulating parasite acetylcholinesterase in human and rodent filariasis. Parasitological Research 78: 671-676
94. Selkirk, M.E., Gregory, W.F., Jenkins, R.E. & Maizels, R.M. (1993) Localisation, turnover and conservation of gp15/400 in different stages of Brugia malayi. Parasitology 107: 449-457
95. Tweedie, S.A.R., Paxton, W.A., Ingram, L., Maizels, R.M., McReynolds, L.A. and Selkirk, M.E. (1993) A surface-associated glycoprotein (gp15/400) from Brugia filarial parasites is composed of multiple tandemly-repeated units and processed from a 400 kDa precursor. Experimental Parasitology 76: 156-164
96. Yazdanbakhsh, M., Paxton, W. A., Kruize, Y. C. M., Sartono, E., Kurniawan, A., van het Wout, A., Selkirk, M. E., Partono, F. & Maizels, R. M. (1993). T cell responsiveness correlates with antibody isotype levels in clinical and asymptomatic lymphatic filariasis. Journal of Infectious Diseases 167: 925-931.
97. Yazdanbakhsh, M., Sartono, E., Kruize, Y., van der Pouw-Kraan, T., van der Meide, P.H., Selkirk, M.E., Hintzen, R.Q., van Lier, R.A.W., and Maizels, R.M. (1993) Elevated levels of T cell activation antigen CD27 and increased Interleukin-4 production in human lymphatic filariasis. European Journal of Immunology 23 : 3312-3317
1994
98. Lawrence, R.A., Allen, J.E., Osborne, J. and Maizels, R.M. (1994) Adult and microfilarial stages of the filarial parasite Brugia malayi stimulate contrasting cytokine and immunoglobulin isotype responses in BALB/c mice. Journal of Immunology 153 : 1216-1224
99. Trenholme, K.R., Tree, T.I.M., Gillespie, A.J., Guderian, R., Maizels, R.M. and Bradley, J.E. (1994) Heterogeneity of IgG antibody responses to cloned Onchocerca volvulus antigens in microfilardermia positive individuals from Esmeraldas Province, Ecuador. Parasite Immunology 16 : 201-209
1995
100. Allen, J.E., Lawrence, R.A. and Maizels, R.M. (1995) Fine specificity of the genetically controlled immune response to native and recombinant gp15/400 (polyprotein allergen) of Brugia malayi. Infection and Immunity63: 2892-2898
101. Maizels, R.M., Sartono, E., Kurniawan, A., Selkirk, M.E., Partono, F. and Yazdanbakhsh, M. (1995) T cell activation and the balance of antibody isotypes in human lymphatic filariasis. Parasitology Today 11: 50-56
102. Gems, D.H., Ferguson, C.J., Robertson, B.D., Page, A.P., Nievos, R., Blaxter, M.L. and Maizels, R.M. (1995) An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26 kDa antigen with homology to phosphatidylethanolamine-binding proteins. Journal of Biological Chemistry 270: 18517-18522.
103. Kurniawan, A., Atkinson, R., Sartono, E., Partono, F., Yazdanbakhsh, M. and Maizels, R.M. (1995) Differential decline in filarial-specific IgG1, IgG4 and IgE antibodies in Brugia malayi–infected patients following diethylcarbamazine chemotherapy. Journal of Infectious Diseases 172: 1567-1572
104. Lawrence, R.A., Allen, J.E., Gregory, W.F., Kopf, M. and Maizels, R.M. (1995) Infection of IL-4 deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a Th2 dominated immune response. Journal of Immunology 154 : 5995-6001
105. Sartono, E., Kruize, Y.C.M., Kurniawan, A., van der Meide, P.H., Partono, F., Maizels, R.M. and Yazdanbakhsh, M. (1995) Elevated cellular immune responses and IFN-g release after long-term DEC treatment of human lymphatic filariasis patients. Journal of Infectious Diseases 171: 1683-1687
106. Sartono, E., Kruize, Y.C.M., Partono, F., Kurniawan, A., Maizels, R.M. and Yazdanbakhsh, M. (1995) Specific T cell unresponsiveness in human filariasis: diversity in underlying mechanisms. Parasite Immunology 17: 587-594
107. Yazdanbakhsh, M., Sartono, E., Kruize, Y.C.M., Kurniawan, A., Partono, F., Maizels, R.M., Schreuder, G.M.T., D’amaro, J., Schippers, R. and de Vries, R.R.P. (1995) HLA and elephantiasis in lymphatic filariasis. Human Immunology 54: 58-61.
108. Yazdanbakhsh, M., Paxton, W.A., Brandenburg, A., van Ree, R., Lens, M., Partono, F., Maizels, R.M. and Selkirk, M.E. (1995) Differential antibody isotype reactivity to specific antigens in human lymphatic filariasis : Gp15/400 preferentially induces IgE, IgG4 and IgG2. Infection and Immunity 63 : 3772-3779
1996
109. Allen, J.E., Lawrence, R.A. and Maizels, R.M. (1996) Antigen presenting cells from mice harboring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. International Immunology 8: 143-151
110. Allen, J.E. and Maizels, R.M. (1996) Immunology of helminth infections in humans. International Archives of Allergy and Immunology 109 : 3-10
111. Burkot, T.R., Kwan-Lim, G.-E. and Maizels, R.M. (1996) A novel 95-kilodalton antigen of Wuchereria bancrofti infective larvae identified by species-specific monoclonal antibodies. Infection and Immunity 64 : 485-488
112. Gems, D.H. and Maizels, R.M. (1996) An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. Proceedings of the National Academy of Sciences 93: 1665-1670
113. Holmes, B.J., Diaz-Sanchez, D., Lawrence, R.A., Bell, E.B., Maizels, R.M. and Kemeney, D.M. (1996) The contrasting effects of CD8+ cells on primary, established and Nippostrongylus brasiliensis-induced IgE responses. Immunology 88: 252-260
114. Lawrence, R.A., Gray, C., Osborne, J. and Maizels, R.M. (1996) Nippostrongylus brasiliensis: T helper subset responses and nematode expulsion in normal and IL4-deficient mice. Experimental Parasitology 84 : 65-73
115. Murdoch, M.E., Abiose, A., Garate, T., Hay, R.J., Jones, B.R., Maizels, R.M. and Parkhouse, R.M.E. (1996) Nigerian human onchocerciasis: IgG subclass antibody responses and antigen recognition in individuals with defined cutaneous pathology. American Journal of Tropical Medicine and Hygiene 54 : 600-612
116. Sartono, E., Kruize, Y.C.M., Kurniawan, A., Maizels, R.M. and Yazdanbakhsh, M. (1996) In Th2 biased lymphatic filarial patients, responses to PPD remain Th1. European Journal of Immunology 26 : 501-504.
117. Yazdanbakhsh, M., Sartono, E., Selkirk, M.E. and Maizels, R.M. (1996) T cell activation and antibody responses in lymphatic filariasis. In T-Cell Subsets and Cytokines Interplay in Infectious Diseases (eds: Mustafa, A.S., Al-Attiya, R.J., Nath, I. & Chugh, T.D.) S.Karger AG, Basel, pp 153-168
1997
118. Allen, J.E. and Maizels, R.M. (1997) Th1 and Th2: reliable paradigm or dangerous dogma ? Immunology Today 18 : 387-392
119. Gomez-Escobar, N., van den Biggelaar, A. and Maizels, R.M. (1997) A member of the TGF-b receptor gene family in the parasitic nematode Brugia malayi. Gene 199: 101-109
120. Gregory, W.F., Blaxter, M.L. and Maizels, R.M. (1997) Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. Molecular and Biochemical Parasitology 87: 85-95
121. Murdoch, M.E., Payton, A., Abiose, A., Thomson, W., Panicker, V.K., Dyer, P., Jones, B.R., Maizels, R.M. and Ollier, W. (1997) HLA-DQ alleles associate with cutaneous features of onchocerciasis. Human Immunology 55: 46-52
122. Sartono, E., Kruize, Y.C.M., Kurniawan-Atmadja, A., van der Meide, P.H., Maizels, R.M. and Yazdanbakhsh, M. (1997) Depression of antigen-specific interleukin-5 and interferon-g responses in human lymphatic filariasis as a function of clinical status and age. Journal of Infectious Diseases 175 : 1276-1280.
123. Sartono, E., van Eggermond, M.C.J.A., Kurniawan, A., Maizels, R.M., van den Elsen, P.J. and Yazdanbakhsh, M. (1997) Selective usage of defined TCRBV genes in response to filarial antigens. International Immunology 9: 955-962
1998
124. Gomez-Escobar, N., Lewis, E. and Maizels, R.M. (1998) A novel member of the transforming growth factor-b(TGF-b) superfamily from the filarial nematodes Brugia malayi and B. pahangi. Experimental Parasitology 88: 200-209
125. Kurniawan, A., Sartono, E., Partono, F., Yazdanbakhsh, M. and Maizels, R.M. (1998) Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunology 20: 9-17
126. Kurniawan, A., Sartono, E., Partono, F., Yazdanbakhsh, M. and Maizels, R.M. (1998) Specificity of predominant IgG4 antibodies to adult and microfilarial stages of Brugia malayi. Parasite Immunology 20: 155-162
127. Loukas, A.C. and Maizels, R.M. (1998) Cloning and characterization of a prohibitin gene from infective larvae of the parasitic nematode Toxocara canis. DNA Sequence 67: 1-6.
128. Loukas, A.C., Selzer, P.M. and Maizels, R.M. (1998) Characterisation of Tc-cpl-1, a cathepsin L-like cysteine proteinase from Toxocara canis infective larvae. Molecular and Biochemical Parasitology 92: 275-289
129. MacDonald, A.S., Maizels, R.M., Lawrence, R.A., Dransfield, I. and Allen, J.E. (1998) Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. Journal of Immunology 160 : 1304-1312
130. Maizels, R.M. and Holland, M.J. (1998) Parasite immunity: pathways for expelling intestinal helminths. Current Biology 8 : R711-R714
1999
131. Loukas, A., Hunt, P. and Maizels, R.M. (1999) Cloning and expression of an aquaporin-like gene from a parasitic nematode. Molecular and Biochemical Parasitology 99: 287-293
132. Loukas, A., Mullin, N.P., Tetteh, K.K.A., Moens, L. and Maizels, R.M. (1999) A novel member of the C-type lectin gene family encodes the major secretory product of a tissue-dwelling parasitic nematode. Current Biology 9 : 825-828
133. Maizels, R.M., Holland, M., Falcone, F., Zang, X.X. and Yazdanbakhsh, M. (1999) Vaccination against helminth parasites : the ultimate challenge for immunologists? Immunological Reviews 171 :125-148
134. Sartono, E., Lopriore, C., Kruize, Y.C.M., Kurniawan-Atmadja, A., Maizels, R.M. and Yazdanbakhsh, M. (1999) Reversal in microfilarial density and T cell responses in human lymphatic filariasis. Parasite Immunology 21: 565-571
135. Tetteh, K.K.A., Loukas, A., Tripp, C. and Maizels, R.M. (1999) Identification of abundantly-expressed, novel and conserved genes from the infective larval stage of Toxocara canis by an EST strategy. Infection and Immunity 67: 4771-4779
136. Zang, X.X., Yazdanbakhsh, M., Kiang, H., Kanost, M.R. and Maizels, R.M. (1999) A novel serpin expressed by the blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood 94 : 1418-1428
2000
137. Falcone, F., Tetteh, K.K.A., Hunt, P., Blaxter, M.L. Loukas, A. and Maizels, R.M. (2000) The new subfamily of cathepsin Z-like protease genes includes Tc-cpz-1, a cysteine protease gene expressed in Toxocara canisadults and infective stage larvae. Experimental Parasitology 94: 201-207
138. Gomez-Escobar, N., Gregory, W.F. and Maizels, R.M. (2000) Identification of Bm-tgh-2, a filarial nematode homolog of C.elegans daf-7 and human TGF-b, expressed in microfilarial and adult stages of Brugia malayi. Infection and Immunity 68 : 6402-6410
139. Gregory, W.F., Atmadja, A.K., Allen, J.E. and Maizels, R.M. (2000) The abundant larval transcript-1 and -2genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infection and Immunity68: 4174-4179
140. Holland, M.J., Harcus, Y.M., Riches, P.L. and Maizels, R.M. (2000) Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. European Journal of Immunology 30: 1977-1987
141. Loke, P., MacDonald, A.S., Robb, A., Maizels, R.M. and Allen, J.E. (2000) Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell to cell contact. European Journal of Immunology 30: 2669-2678
142. Loukas, A. and Maizels, R.M. (2000) Helminth C-type lectins and host-parasite interactions. Parasitology Today 16 : 333-339
143. Loukas, A., Doedens, A., Hintz, M. and Maizels, R.M. (2000) Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host endothelial cells. Parasitology 121: 545-554
144. Loukas, A.C., Hintz, M., Linder, D., Mullin, N.P., Parkinson, J., Tetteh, K.K.A. and Maizels R.M. (2000) A family of secreted mucins from the parasitic nematode Toxocara canis bear diverse mucin domains but share similar flanking six-cysteine (SXC) repeat motifs. Journal of Biological Chemistry 275 : 39600-39607
145. Maizels, R.M., Allen, J.E. and Yazdanbakhsh, M. (2000) Immunology of Lymphatic Filariasis : Current Controversies. In Lymphatic Filariasis (ed. Nutman T.B.), Imperial College Press, pp 217-243
146. Maizels, R.M., Tetteh, K.K.A. and Loukas, A. (2000) Toxocara canis : Genes expressed by the arrested infective larval stage of a parasitic nematode. International Journal of Parasitology 30: 495-508
147. Zang, X.X., Kurniawan, A.K., Gray, P., Allen, J.E., Gray, C., Lawrence, R.A., Yazdanbakhsh, M. and Maizels, R.M. (2000) The serpin secreted by Brugia malayi microfilariae, Bm-SPN-2, elicits strong but short-lived immune responses in mice and humans. Journal of Immunology 165: 5161-5169