Mentors

I have been remarkably fortunate to have had extraordinary mentors during my early career:

David Dresser in the Division of Immunology at NIMR, Mill Hill. David pioneered models of immunological tolerance (Dresser and Mitchison 1968) leading to the “two-signal” hypothesis of lymphocyte activation.

David passed away early in 2020. Here is my memoir for his memorial : David Dresser, memoir by Rick Maizels

Ray Owen at the California Institute of Technology (CalTech)

Eli Sercarz at University of California Los Angeles (UCLA)

Bridget Ogilvie in the Division of Parasitology at NIMR, Mill Hill

In later years, David joined the Maizels Lab in Edinburgh with funding from the INNW (If Not Now When?) Foundation to study Anti-Müllerian Hormone, a member of the TGF-β family, shown in the following publications:

Dresser, D.W. (2014). The Transcription Factors GATA-1 and GATA-4 have opposite effects on DNA expression drivers by an Amh promoter.  American Journal of Molecular Biology 4, (150-158).

Dresser, D.W. (2013). Interaction betweeen the Wilms tumour factor-1 element in the promoter of Amh and a downstream enhancer is required for a strong expression of the gene in pre-pubertal sertoli cells. American Journal of Molecular Biology 3, online

Dresser, D.W. (2012). Mutated elements of a complex promoter (Amh) can help to demonstrate the role of certain elements in controlling differential gene expression. American Journal of Molecular Biology 2, (351-358).