Just published ! A major review on TGF-β mimics and Cytokines from Parasites : Maizels RM, McSorley HJ, Smits HH, ten Dijke P, Hinck AP (2025) Cytokines from parasites: Manipulating host responses by molecular mimicry. Biochem J 482: 1-18. PDF […]
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Exciting new paper led by Andy Hinck’s lab on TGM6 is now available online Doi is https://doi.org/10.1038/s41467-025-56954-z.
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An exciting new collaborative project, funded by a Wellcome Discovery Award, is starting in Rick Maizels’ lab, together with leading figures in the area of helminth immunology (Henry McSorley, University of Dundee and Hermelijn Smith, Leiden University Medical Center) and […]
Read moreWe are excited to see our new paper, first authored by Shashi Singh, on how TGM4 has preference for myeloid cell activation through an extended set of co-receptors: download the PDF here ! Singh, S.P., Smyth, D.J., Cunningham, K.T., Mukundan, […]
Read moreOur collaboration with Philippe Jay at INSERM in Montpellier has continued with a new publication in Immunity, Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity, by Marième Ndjim et al – click here for link to […]
Read moreAugust 2023 : Exciting new data showing that TGM1 (H. polygyrus Transforming Growth factor-beta Mimic-1) binds not only the mammalian TGFβ receptors (as shown by Mukundan et al, 2022, doi 10.1016/j.jbc.2022.101994), but also CD44, enhancing potency for induction of regulatory T […]
Read moreRick Maizels’ commentary on the great paper By Shinoda et al (https://doi.org/10.1073/pnas.2108686119), is now published ! Open Access Commentary on PNAS website here. Maizels, R.M. (2022) Ascarosides from helminths pack a punch against allergy. Proc Natl Acad Sci USA 119: e2202250119.
Read moreFumi Varyani’s paper on the role of MIF in innate immunity to Nippostrongylus brasiliensis infection is now out in Mucosal Immunity! The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF) –Open Access – click […]
Read moreDrurey, C., Lindholm, H., Coakley, G., Campillo Poveda, M., Loeser, S., Doolan, R., Gerbe, F., Jay, P., Harris, N., Oudhoff, M.J. and Maizels, R.M. (2022) Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products.
Read moreRick Maizels was recently interviewed by Finding Genius with a podcast available through various sites including the Finding Genius website, and Apple Podcasts through iTunes. Or you can reach it quickly here : And here is the summary from Finding […]
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