Category Archives: Uncategorized

August 2023 : Exciting new data showing that TGM1 (H. polygyrus Transforming Growth factor-beta Mimic-1) binds not only the mammalian TGFβ receptors (as shown by Mukundan et al, 2022, doi 10.1016/j.jbc.2022.101994), but also CD44, enhancing potency for induction of regulatory T cells. The outcome of a great collaboration with the laboratories of Peter ten Dijke (Leiden…

Rick Maizels' commentary on the great paper By Shinoda et al (https://doi.org/10.1073/pnas.2108686119), is now published ! Open Access Commentary on PNAS website here. Maizels, R.M. (2022) Ascarosides from helminths pack a punch against allergy. Proc Natl Acad Sci USA 119: e2202250119.

Fumi Varyani's paper on the role of MIF in innate immunity to Nippostrongylus brasiliensis infection is now out in Mucosal Immunity! The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF) -Open Access - click here for PDF link

Drurey, C., Lindholm, H., Coakley, G., Campillo Poveda, M., Loeser, S., Doolan, R., Gerbe, F., Jay, P., Harris, N., Oudhoff, M.J. and Maizels, R.M.  (2022) Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products.

Rick Maizels was recently interviewed by Finding Genius with a podcast available through various sites including the Finding Genius website, and Apple Podcasts through iTunes. Or you can reach it quickly here : https://bit.ly/33Ueee8 And here is the summary from Finding Genius: Parasites are a neglected area of medicine and Rick Maizels is working to…

Rick Maizels has been recognised as a "Highly Cited Researcher" by the Web of Science for 2020, having published multiple highly-cited papers ranking in the top 1% of citations for field and year.

Two Post-Doctoral Research Positions in the Maizels Lab at the University of Glasgow We are advertising 2 posts in Rick Maizels’ lab within the Wellcome Centre for Integrative Parasitology (WCIP), at Glasgow University’s Institute for Infection, Immunity and Inflammation (3is). Both are funded through grants from the Wellcome Trust, and the post-holders will join a group…

A new comprehensive review on molecular mediators from helminths has been co-authored by Rick Maizels, Hermelijn Smits (Leiden University Medical Center) and Henry McSorley (University of Edinburgh). Maizels RM, Smits HH, & McSorley HJ (2018) Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules. Immunity 49(5):801-818. DOI:https://doi.org/10.1016/j.immuni.2018.10.016 Open access here !

A short article on recent papers showing neuromedin U links the nervous and innate immune systems - Löser, S. and Maizels, R.M. (2018) Immunology: the nervous pathway to mucosal immunity. Current Biology 17: R33-R36 Download PDF

Two Major New Papers out at the end of 2017 ! Johnston, C.J.C., Smyth, D.J., Kodali, R.B., White, M.P.J., Harcus, Y., Filbey, K.J., Hewitson, J.P., Hinck, C.S., Ivens, A., Kemter, A.M., Kildemoes, A.O., Le Bihan, T., Soares, D., Anderton, S.M., Brenn, T., Wigmore, S.J., Woodcock, H., Chambers, R.C., Hinck, A.P., McSorley, H.J. and Maizels, R.M.…