Publications in 2025
375. Campillo-Poveda, M., Löser, S., Gillan, V., Richards, J., Ciancia, C., Blackburn, G., Kerr, E. Barrett, M.. Hildersley, K., Jay, P., Devaney, E., McNeilly, T., Britton, C. and Maizels, R.M. (2025) Metabolomic and functional analyses of small molecules secreted by intestinal nematodes in the activation of epithelial tuft cells. Metabolomics 21(3): 55. Open Access PDF on Publisher’s Website.
376. Fahs, H., Refai, F.S., Gopinadhan, S., Moussa, Y., Gan, H.H., Hunashal, Y., Battaglia, G., Cipriani, P.G., Ciancia, C., Rahiman, N., Kremb, S., Xie, X., Pearson, Y., Butterfoss, G.L., Maizels, R.M., Esposito, G., Page, A.P. , Gunsalus, K.C. , and Piano, F. (2025) A new class of natural anthelmintics targeting lipid metabolism. Nature Communications 16:305 Open Access PDF on Publisher’s Website
377. Grigg, J., Barratt, B., Bønnelykke,K. , Custovic, A. , Ege, M. , Pasquali, C., Palomares O., Shaheen, S , Sokolowska, M., Vercelli, D., Maizels, R. and von Mutius, E. (2025) European Respiratory Society Research Seminar on preventing paediatric asthma. Pediatric Pulmonology 60:e27401. Open Access PDF on Publisher’s Website
378. Maizels, R.M., McSorley, H.J., Smits, H.H., ten Dijke, P. and Hinck, A.P. (2025) Cytokines from parasites: Manipulating host responses by molecular mimicry. Biochemical Journal, 482: 1-18. PDF available here.
379. Neophytou, K., Martínez-Ugalde, I., Fenton, T., Robertson, E., Strachan, L.J., Jayaraman, V., Harcus, Y., Naar, C.M., Wright, D., Price, D.R.G., White, R., Evans, M.J., Bermúdez-Barrientos, J.R., Li, H., Maizels, R.M., Aroian, R.V., Nisbet, A.J., Abreu-Goodger, C. and Buck, A.H. (2025). An Argonaute protein traffics from nematode to mouse and is a vaccine against parasitic nematodes. EMBO Reports, 10.1038/s44319-025-00620-4 Open Access PDF on Publisher’s Website.
380. Ntang, E.Y., Cunningham, K.T., Singh, S.P., Ciancia, C., Sanders, A., Lilla, S., Mukundan, A., Ghogomu, S.M, Hinck, A. and Maizels, R.M. (2025) Structural and functional analysis of the TGF-β mimic TGM-2: an immunomodulatory helminth protein. Genes and Immunity. Open Access PDF on Publisher’s Website
381. Perez, M.G., Gillan, V., Anderson, W., Gerbe, F., Herbert, F., McNeilly, T.N., Maizels, R.M., Jay, P., Devaney, E. and Britton, C. (2025). A secreted helminth microRNA modulates gastrointestinal gene expression and suppresses cell differentiation required for innate immunity. Frontiers in Immunology, 16: 1558132 Open Access PDF on Publisher’s Website
382. Shek, V., Jamwal, A., Frangova, T., Savage, A.R., Kelly, S., Smyth, D.J., Wright, G.J., Toth, R., Ivens, A.C., Maizels, R.M., Higgins, M.K., Smits, H.H. and McSorley, H.J. (2025) HpBoRB, a helminth-derived CCP domain protein which binds RELMβ. International Journal of Parasitology. doi.org/10.1016/j.ijpara.2025.09.006. Open Access PDF on Publisher’s Website
383. Singh, S.P., Smyth, D.J., Cunningham, K.T., Mukundan, A., Byeon, C.-H., Hinck, C.S., White, M.P.J., Ciancia, C., Wasowska, N., Sanders, A., Jin, R., White, R.F., Lilla, S., Zanivan, S., Schoenherr, C., Inman, G.J., van Dinther, M., ten Dijke, P., Hinck, A.P. and Maizels, R.M. (2025) The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding. EMBO Reports 26: 218-244. doi 10.1038/s44319-024-00323-2 . Open Access PDF on Publisher’s Website
384. Smyth, D.J., Hodge, S.J., Ong, N.W.P., Richards, J. Colomb, F., Di Carmine, S., Shek, V., Frangova, T., Campillo Poveda, M., Maizels, R.M. and McSorley, H.J. (2025) Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection. Cell Reports 44: 115721 Open Access PDF on Publisher’s Website
385. White, S.E, Schwartze, T.A., Mukundan, A., Schoenherr, C., Singh, S., van Dinther, M., Cunningham, K., White, M.P.J., Campion, T., Pritchard, J., Hinck, C.S., ten Dijke, P., Inman, G., Maizels, R.M. and Hinck, A.P. (2025) TGM6 is a helminth secretory product that mimics TGF-β binding to TβRII to antagonize signaling in fibroblasts. Nature Communications 10.1101/2023.12.22.573140. Open Access PDF on Publisher’s Website
386. Zumbado-Salas, M., Rojas, A., Maizels, R.M. and Mora, J. (2025) Cross-species immunomodulation by zoonotic helminths: the roles of excretory/secretory products and extracellular vesicles. In Extracellular Vesicles Advances and Perspectives in Treatments, Therapies and Vaccination, Academic Press (Eds Torrecilhas, A.C., de Oliveira Andrade, L., and Kushmerick, C. PDF of Chapter Available Here. For purchase of whole book use this link.