Lab Publications 2025 (375- )

Publications in 2025

375.  Campillo-Poveda, M., Löser, S., Gillan, V., Richards, J., Ciancia, C., Blackburn, G., Kerr, E. Barrett, M.. Hildersley, K., Jay, P., Devaney, E., McNeilly, T., Britton, C. and Maizels, R.M.  (2025) Metabolomic and functional analyses of small molecules secreted by intestinal nematodes in the activation of epithelial tuft cells. Metabolomics in press

376. Fahs, H., Refai, F.S., Gopinadhan, S., Moussa, Y., Gan, H.H., Hunashal, Y., Battaglia, G., Cipriani, P.G., Ciancia, C., Rahiman, N., Kremb, S., Xie, X., Pearson, Y., Butterfoss, G.L., Maizels, R.M., Esposito, G., Page, A.P. , Gunsalus, K.C. , and Piano, F.   (2025) A new class of natural anthelmintics targeting lipid metabolism. Nature Communications 16:305 Open Access PDF on Publisher’s Website

377.  Grigg, J., Barratt, B., Bønnelykke,K. , Custovic, A. , Ege, M. , Pasquali, C., Palomares O., Shaheen, S , Sokolowska, M., Vercelli, D., Maizels, R. and von Mutius, E. (2025) European Respiratory Society Research Seminar on preventing paediatric asthma. Pediatric Pulmonology 60:e27401. Open Access PDF on Publisher’s Website

378. Maizels, R.M., McSorley, H.J., Smits, H.H., ten Dijke, P. and Hinck, A.P. (2025) Cytokines from parasites: Manipulating host responses by molecular mimicry. Biochemical Journal, in press

379. Perez, M.G., Gillan, V., Anderson, W., Gerbe, F., Herbert, F., McNeilly, T.N., Maizels, R.M., Jay, P., Devaney, E. and Britton, C. (2025). A secreted helminth microRNA modulates gastrointestinal gene expression and suppresses cell differentiation required for innate immunity. Frontiers in Immunology, in press

380. Singh, S.P., Smyth, D.J., Cunningham, K.T., Mukundan, A., Byeon, C.-H., Hinck, C.S., White, M.P.J., Ciancia, C., Wasowska, N., Sanders, A., Jin, R., White, R.F., Lilla, S., Zanivan, S., Schoenherr, C., Inman, G.J., van Dinther, M., ten Dijke, P., Hinck, A.P. and Maizels, R.M. (2025) The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding. EMBO Reports 26: 218-244. doi 10.1038/s44319-024-00323-2 . Open Access PDF on Publisher’s Website

381. Smyth, D.J., Hodge, S.J., Ong, N.W.P., Richards, J. Colomb, F., Di Carmine, S., Shek, V., Frangova, T., Campillo Poveda, M., Maizels, R.M. and McSorley, H.J. (2025) Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection. Cell Reports in press

382.  White, S.E, Schwartze, T.A., Mukundan, A., Schoenherr, C., Singh, S., van Dinther, M., Cunningham, K., White, M.P.J., Campion, T., Pritchard, J., Hinck, C.S., ten Dijke, P., Inman, G., Maizels, R.M. and Hinck, A.P. (2025) TGM6 is a helminth secretory product that mimics TGF-β binding to TβRII to antagonize signaling in fibroblasts. Nature Communications 10.1101/2023.12.22.573140. Open Access PDF on Publisher’s Website