Maizels Lab Publications 1977-1990 (1-65)


1.      Maizels, R.M., and Dresser, D.W. (1977)  Conditions for the development of IgM- and IgG-  antibody-secreting cells from primed mouse splenocytes in vitro.  Immunology  32: 793-801

2.      North, J. R., and Maizels, R.M. (1977)  B-memory cells can be stimulated by antigen  in vitro  to become IgG antibody-secreting cells.    Immunology 32:771-776.


3.      Maizels, R.M., Frelinger, J. A., and Hood, L. (1978)  Partial amino acid sequences of mouse transplantation antigens.  Immunogenetics  7: 425-444


4.      Maizels, R.M., Clarke, J.A., Harvey, M.A., Miller, A., and Sercarz, E.E. (1980)  Epitope specificity of the T-cell proliferative response to lysozyme:  T-proliferative cells react predominantly to different determinants from those recognised by B cells.  European Journal of Immunology  10: 509-515

5.      Maizels, R.M., Clarke, J.A., Harvey, M. A., Miller, A. and Sercarz, E. E. (1980)  Ir gene control of T cell proliferative responses:  Two distinct expressions of the genetically non-responsive state.  European Journal of Immunology 10: 516-520

6.      Ogilvie, B.M., Philipp, M., Jungery, M., Maizels, R.M., Worms, M.J. and Parkhouse, R.M.E. (1980)  The surface of nematodes and the immune responses of the host.  In: The Host Invader Interplay   (Ed. Van den Bossche, H.) pp. 99-104.  Elsevier/North-Holland, Amsterdam.


7.      Sercarz, E., Wicker, L., Stratton, J., Miller, A., Metzger, D., Maizels, R. M., Katz, M., Harvey, M. and Benjamin, C. (1981) Regulation of antibody specificty and idiotype by two independent T cells.  ICN-UCLA Symposium on Molecular Biology 20: 533-546 (Eds: Janeway, C., Sercarz, E. E. and Wigzell, H.) Academic Press, New York.


8.      Katz, M. E., Maizels, R. M., Wicker, L., Miller, A. and Sercarz, E. E. (1982)  Immunological focusing by the mouse major histocompatibility complex: Mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes.  European Journal of Immunology 12: 535-540

9.      Maizels, R. M., Philipp, M. and Ogilvie, B. M. (1982) Molecules on the surface of parasitic nematodes as probes of the immune responses in infection.  Immunological Reviews  61: 109-136

10.    Ogilvie, B. M., Maizels, R. M. and Philipp, M. (1982)  Surface antigens of nematodes and the immune response of the host.  Fortschritte der Zoologie  27: 113-116


11.    Katz, M. E., Miller, A., Kryzch, U., Wicker, L., Maizels, R. M., Clarke, J., Shastri, N., Oki, A. and Sercarz, E. E. (1983)  Hierarchical relationships among epitopes:  Only certain potentially utilizable epitopes on protein antigens are actually presented in a particular haplotype.  In: Ir Gene: Past, Present and Fututre, ed. Pierce, C. W., Cohen, S. E., Kapp, J. A., Schwartz, B. D. and Schreffler, D. C., pp 311, Clifton, N. J., Humana.

12.    Maizels, R. M., Meghji, M. and Ogilvie, B. M. (1983)  Restricted sets of parasite antigens from the surface of different stages and sexes of the nematode Nippostrongylus brasiliensis.   Immunology  48: 107-121

13.    Maizels, R. M., Partono, F., Oemijati, S. and Ogilvie, B. M. (1983)  Antigenic analysis of Brugia timori , a filarial nematode of man: Initial characterisation by surface radio-iodination and evaluation of diagnostic potential.  Clinical and Experimental Immunology  51: 269-277

14.    Maizels, R. M., Partono, F., Oemijati, S., Denham, D. A. and Ogilvie, B. M. (1983)  Cross-reactive surface antigens on three stages of Brugia malayi , B.pahangi  and B.timori.  Parasitology  87:  249-263


15.    Maizels, R. M. and Meghji, M. (1984)  Repeated patent infection of adult dogs with Toxocara canis.  Journal of Helminthology  58:  327-333

16.    Maizels, R. M., Philipp, M., Dasgupta, A. and Partono, F. (1984)  Human serum albumin is a major component on the surface of microfilariae of Wuchereria bancrofti.  Parasite Immunology  6:  185-190

17.    Maizels, R. M., de Savigny, D and Ogilvie, B. M (1984) Characterisation of surface and excretory- secretory antigens of Toxocara canis  infective larvae.  Parasite Immunology  6: 23-37

18.    Philipp, M., Worms, M. J., Maizels, R. M. and Ogilvie, B. M. (1984)  Rodent models of filariasis.  Contemporary Topics in Immunobiology 12: 275-321 (Ed. Marchalonis, J.J.) Plenum Press, New York.

19.    Pritchard, D. I., Maizels, R. M., Behnke, J. M. and Appleby, P. (1984)  Stage-specific antigens of Nematospiroides dubius.  Immunology  53:  325-335


20.    Maizels, R. M., Denham, D. A. and Sutanto, I. (1985)  Secreted and circulating antigens in the filarial parasite Brugia pahangi:  Analysis of in vitro  released components and detection of parasite products in vivo.  Molecular and Biochemical Parasitology  17:  277-288

21.    Maizels, R. M., Sutanto, I., Gomez-Priego, A., Lillywhite, J  and Denham, D. A. (1985)  Specificity of surface molecules of adult Brugia  parasites: cross reactivity with antibody from WuchereriaOnchocerca and other human filarial infections.  Tropical Medicine and Parasitology 36 : 233-237

22.    Parkhouse, R. M. E., Clarke, N. W. T., Maizels, R. M. and Denham, D. A. (1985)  Brugia pahangi :   Labelling of secreted antigens with 35S-methionine in vitro.  Parasite Immunology 7: 665-668

23.    Sutanto, I., Maizels, R. M. and Denham, D. A. (1985)  Surface antigens of a filarial nematode:  Analysis of adult Brugia pahangi  surface components and their use in monoclonal antibody production.  Molecular and Biochemical Parasitology 15: 203-214


24.    Fattah, D. I., Maizels, R. M., McLaren, D. J. and Spry, C. J. F. (1986)  Interaction of human blood eosinophils with Toxocara canis  larvae in vitro.  Experimental Parasitology  61: 421-433 

25.    Maizels, R. M., Burke, J., Sutanto, I., Purnomo and Partono, F. (1986)  Secreted and surface antigens from the larval stages of Wuchereria bancrofti, the major human lymphatic filarial parasite.  Molecular and Biochemical Parasitology  19: 27-34

26.    Meghji, M. and Maizels, R. M. (1986)  Biochemical properties of larval excretory- secretory (ES) glycoproteins of the parasitic nematode Toxocara canis.  Molecular and Biochemical Parasitology  18: 155-170

27.    Morgan, T. M., Sutanto, I., Purnomo, Sukartono, Partono, F. and Maizels, R. M. (1986)  Antigenic characterisation of adult Wuchereria bancrofti filarial nematodes.  Parasitology  93: 559-569

28.    Philipp, M., Maizels, R. M., McLaren, D. J., Davies, M. W., Suswillo, R. and Denham, D. A. (1986)  Expression of cross-reactive surface antigens by different stages of Brugia pahangi during infections in cats.   Transactions of the Royal Society of Tropical Medicine and Hygiene  80: 385-393

29.    Selkirk, M. E., Denham, D. A., Partono, F., Sutanto, I. and Maizels, R. M. (1986)  Molecular characterisation of antigens of lymphatic filariae.  Parasitology  91:  S15-S38


30.    Kennedy, M.K.,  Maizels, R.M.,  Meghji, M.,Young, L., Qureshi, F. and Smith, H.V.  (1987)  Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae.   Parasite Immunology  9: 407-420

31.    Maizels, R. and  McKerrow, J.H.  (1987)  Future molecular strategies for the study of nematode, trematode and cestode parasites. In:  Molecular Paradigms for Eradicating Helminthic Parasites - UCLA Symposia on Molecular and Cellular Biology  59 : 561-566.

32.    Maizels, R.M., Bianco, A.E., Burke, J., Flint, J.E., Gregory, W.F., Kennedy, M.W., Lim, G.E.,  Robertson, B.D. and Selkirk, M.E.  (1987)  Glycoconjugate antigens from parasitic nematodes.  In:  Molecular Paradigms for Eradicating Helminthic Parasites - UCLA Symposia on Molecular and Cellular Biology  59 : 267-279.

33.    Maizels, R.M., Burke, J. and  Denham, D.A.  (1987)  Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in vitro  secretions and infection sera of Brugia malayi  and B.pahangi.  Parasite Immunology  9 :  49-66

34.    Maizels, R.M., Kennedy, M.K., Meghji, M., Robertson, B.D. and Smith, H.V.  (1987)  Shared carbohydrate epitopes on distinct surface and secreted antigens of the parasitic nematode Toxocara canis.  Journal of Immunology  139: 207-214

35.    Maizels, R. M., Selkirk, M. E., Sutanto, I. and Partono, F. (1987)  Antibody responses to human lymphatic filarial parasites.  In: Filariasis, Ciba  Foundation Symposium 127, John Wiley, Chichester,pp 189-202

36.    Rathaur, S., Robertson, B.D., Selkirk, M.E. and Maizels, R.M.  (1987)  Secreted acetylcholinesterases from Brugia malayi adult and microfilarial parasites.  Molecular and Biochemical Parasitology  26: 257-265

37.    Robertson, B.D., Rathaur, S. and Maizels, R.M.  (1987)  Antigenic and biochemical analyses of the excretory-secretory molecules of Toxocara canis  infective larvae.  In: Helminth Zoonoses, Eds Geerts, S., Kumar, V. and Brandt, J., Martinus Nijhoff Publishers, Dordrecht, pp 167-174

38.    Selkirk, M.E., Rutherford, P.J.,  Bianco, A.E., Flint, J.E., Denham, D.A., Partono, F. and Maizels, R.M.   (1987)  Characterization and cloning of lymphatic filarial antigens.  In:  Molecular Paradigms for Eradicating Helminthic Parasites - UCLA Symposia on Molecular and Cellular Biology 59 : 169-181.

39.    Selkirk, M.E., Rutherford, P.J., Denham, D.A., Partono, F. and Maizels, R.M.  (1987)  Cloned antigen genes of Brugia filarial parasites.  Biochemical Society Symposia  53 : 91-102


40.    Dinning, W.J., Gillespie, S.H., Cooling, R.J. and Maizels, R.M. (1988) Toxocariasis: A practical approach to management of ocular disease.  Eye 2, 580-582.

41.    Maizels, R.M. and Selkirk, M.E. (1988) Antigens of Filarial Parasites.  ISI Atlas of Science: Immunology 1 : 143-148

42.    Maizels, R. and Selkirk, M.E. (1988)  Immunobiology of nematode antigens. In: The Biology of Parasitism  (Eds. Englund PT  and Sher A)   Alan R. Liss Inc., New York., pp 285-308.

43.    Maizels, R.M., Morgan, T.M., Gregory, W.F., Selkirk, M.E., Purnomo, Sukartono and Partono, F.  (1988) Circulating antibodies and antigens in Presbytis monkeys infected with the filarial parasite Wuchereria bancrofti.  Tropical Medicine and Parasitology  39: 214-220

44.    Robertson , B.D., Kwan-Lim, G.-E. and Maizels, R.M.  (1988)  A sensitive microplate assay for the detection of proteolytic enzymes using radiolabeled gelatin.  Analytical Biochemistry 172 : 284-287

45.    Robertson, B.D., Burkot, T.R., Gillespie, S.H., Kennedy, M.W., Wambai, Z. and Maizels, R.M. (1988)  Detection of circulating parasite antigen and specific antibody in Toxocara canis infections.  Clinical and Experimental Immunology  74: 236-241


46.    Apple, R., Clarke, J., Cogswell, J., Gammon, G., Katz, M.E., Kryzch, U., Maizels, R., Manca, F., Miller, A., Nasseri, S., Oki, A., Wilbur, S. and Sercarz, E.  (1989) The causes and consequences of immunodominance at the T cell level.  In The Immune Response to Structurally Defined Proteins: the Lysozyme Model (Eds, Smith-Gull, S.J. and Sercarz, E.E.), Adenine Press, Schenectady, New York pp 267-277

47.    Bianco, A.E. and Maizels, R.M.  (1989)  Parasite development and adaptive specialization.  Parasitology  99 : S113-S123

48.    Bradley, J.E., Gregory W.F., Bianco, A.E. and Maizels, R.M. (1989) Biochemical and immuno-chemical characterisation of a 20-kilodalton complex of surface–associated antigens from adult Onchocerca gutturosafilarial nematodes.  Molecular and Biochemical Parasitology  34: 197-208.

49.    Burkot, T.R., Graves, P.M., Wirtz, R.A., Brabin, B.J., Battistutta, D., Cattani, J.A., Maizels, R.M. and Alpers, M.P.  (1989)  Differential antibody responses to Plasmodium falciparum and P.vivax circumsporozoite proteins in a human population.  Journal of Clinical Microbiology  27: 1346–1351.

50.    Haswell-Elkins, M.R., Kennedy, M.W., Maizels, R.M., Elkins, D.B. and Anderson, R.M.  (1989)  The antibody recognition profiles of humans naturally infected with Ascaris lumbricoides.    Parasite Immunology  11: 615–627

51.    Helm, R., Selkirk, M.E., Bradley, J.E., Burns, R.G., Hamilton, A.J., Croft, S. and Maizels, R.M.  (1989) Localisation and immunogenicity of tubulin in the filarial nematodes Brugia malayi and B.pahangi Parasite Immunology  11: 479-502.

52.    Kwan-Lim, G.E., Gregory, W.F., Selkirk, M.E., Partono, F. and Maizels, R.M.  (1989) Secreted antigens of filarial nematodes: survey and characterisation of in vitro excretory/secretory (ES) products of  adult Brugia malayifilarial parasites.  Parasite Immunology  11: 629–654.

53.    Maizels, R.M. , Agnew, A. and Selkirk, M.E.  (1989)  Prospects for new vaccines against helminth parasites.  Trends in Biotechnology  7: 316–321.

54.    Maizels, R.M., Gregory, W.F., Kwan-Lim, G.-E. and Selkirk, M.E.  (1989)  Filarial surface antigens: the major 29,000 mol.wt. glycoprotein and a novel 17,000 - 200,000 mol.wt. complex  from adult Brugia malayi parasites.  Molecular and Biochemical Parasitology  32: 213-227.

55.    Partono, F., Maizels, R.M. and Purnomo. (1989)  Towards a Filariasis free community: Evaluation of filariasis control over a 11 year period in Flores, Indonesia.  Transactions of the Royal Society of Tropical Medicine and Hygiene  83: 821–826.

56.    Robertson, B.D, Bianco,  A.E., McKerrow, J.H. and Maizels, R.M.  (1989)  Proteolytic enzymes secreted by larvae of the nematode Toxocara canis.   Experimental Parasitology  69, 30-36.

57.    Selkirk, M.E., Nielsen, L., Kelly, C., Partono, F., Sayers, G. and Maizels, R.M.  (1989)  Identification, synthesis and cross-reactivity of cuticular collagens from the filarial nematodes Brugia malayi and B.pahangi.  Molecular and Biochemical Parasitology  32: 229-246.

58.    Selkirk, M.E., Denham, D.A. Partono, F. and Maizels, R.M. (1989)  Heat shock cognate 70 is a prominent  immunogen in Brugian  filariasis. Journal of Immunology  143:299-308.


59.    Kwan-Lim, G.-E. and Maizels, R.M.  (1990) MHC and non-MHC restricted recognition of filarial surface antigens in mice transplanted with adult Brugia malayi parasites.  Journal of Immunology 145, 1912-1920.

60.    Kwan-Lim, G.-E., Forsyth K.P. and Maizels, R.M. (1990) Filarial-specific IgG4 response correlates with active Wuchereria bancrofti infection. Journal of Immunology 145: 4298-4305.

61.    Maizels, R.M. (1990)  Parasite Antigens.  In Parasites: Immunity and Pathology.  The Consequences of Parasitic Infection in Mammals.  (Ed. Behnke, J.M.) Taylor and Francis Ltd, London, pp 23-41.

62.    Maizels, R.M. and Page, A.P.  (1990)  Surface associated glycoproteins from Toxocara canis L2 parasites.  Acta Tropica  47: 355-364.

63.    Maizels, R.M., Bradley, J.E., Helm, R.  and Karam, M.  (1990)  Immunodiagnosis of onchocerciasis: circulating antigens and antibodies to recombinant peptides.   Acta Leidensia  59: 261-270

64.    Ogilvie, B.M., Selkirk, M.E. and Maizels, R.M.  (1990)  The molecular revolution and nematode parasitology: Yesterday, today and tomorrow.  Journal of Parasitology  76: 607-618.

65.    Selkirk, M.E., Gregory, W.F., Yazdanbakhsh, M., Jenkins, R.E.  and Maizels, R.M.  (1990)  Cuticular localisation and turnover of the major surface glycoprotein (gp29) of adult Brugia malayi.  Molecular and Biochemical Parasitology  42 : 31-44.