New interview in Freethink
Namir Khaliq, journalist with Freethink, has published a commentary including an interview with Rick Maizels
Read moreTwo new papers from the Maizels Lab
Just published ! A major review on TGF-β mimics and Cytokines from Parasites : Maizels RM, McSorley HJ, Smits HH, ten Dijke P, Hinck AP (2025) Cytokines from parasites: Manipulating host responses by molecular mimicry. Biochem J 482: 1-18. PDF […]
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New Paper on TGM6, TGF-β Antagonist, in Nature Communications
Exciting new paper led by Andy Hinck’s lab on TGM6 is now available online Doi is https://doi.org/10.1038/s41467-025-56954-z.
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New Collaborative Project starts in Rick Maizels’ Lab
An exciting new collaborative project, funded by a Wellcome Discovery Award, is starting in Rick Maizels’ lab, together with leading figures in the area of helminth immunology (Henry McSorley, University of Dundee and Hermelijn Smith, Leiden University Medical Center) and […]
Read moreNew Paper on TGM4 in EMBO Reports – Singh et al. (2025)
We are excited to see our new paper, first authored by Shashi Singh, on how TGM4 has preference for myeloid cell activation through an extended set of co-receptors: download the PDF here ! Singh, S.P., Smyth, D.J., Cunningham, K.T., Mukundan, […]
Read moreNew Paper on Tuft Cell Acetylcholine in Immunity
Our collaboration with Philippe Jay at INSERM in Montpellier has continued with a new publication in Immunity, Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity, by Marième Ndjim et al – click here for link to […]
Read moreCD44 coreceptor for TGM1 – published in PNAS
August 2023 : Exciting new data showing that TGM1 (H. polygyrus Transforming Growth factor-beta Mimic-1) binds not only the mammalian TGFβ receptors (as shown by Mukundan et al, 2022, doi 10.1016/j.jbc.2022.101994), but also CD44, enhancing potency for induction of regulatory T […]
Read moreApril 2022 : PNAS Commentary published
Rick Maizels’ commentary on the great paper By Shinoda et al (https://doi.org/10.1073/pnas.2108686119), is now published ! Open Access Commentary on PNAS website here. Maizels, R.M. (2022) Ascarosides from helminths pack a punch against allergy. Proc Natl Acad Sci USA 119: e2202250119.
Read moreMarch 2022 : Paper on MIF (macrophage migration inhibitory factor) in Mucosal Immunology
Fumi Varyani’s paper on the role of MIF in innate immunity to Nippostrongylus brasiliensis infection is now out in Mucosal Immunity! The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF) –Open Access – click […]
Read moreJanuary 2022 : Paper on H. polygyrus inhibition of Tuft Cell development, published in J Exp Med
Drurey, C., Lindholm, H., Coakley, G., Campillo Poveda, M., Loeser, S., Doolan, R., Gerbe, F., Jay, P., Harris, N., Oudhoff, M.J. and Maizels, R.M. (2022) Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products.
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